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Data incubator scholar finalist11/6/2023 “This research aims to access an indolizidine precursor through an efficient and diversifiable route,” Gillen says. They offer a range of known and unknown biological applications when functionalized, but they are not easily or affordably accessed. Gillen will research indolizidine alkaloids, a class of biologically active organic molecules. Working with Cannon, himself a former Science Scholar at Occidental, Gillen’s project is called “A novel approach for the stereoselective synthesis of the Indolizidine Alkaloids.” ![]() We propose that an electrode and potentiostat could fill the role of NAD(P)H and the P450 Reductase domains in the two-electron reduction of the enzyme,” Dearden says. “To address this issue, our research explores the electrochemical reduction of P450 as an alternative to NAD(P)H. ![]() But accessing this molecular engineering tool requires a reduction of NAD(P)H via oxidation, a very expensive process. “Learning about methane-consuming symbiotic relationships and systems in the deep sea may provide insight into how to manage carbon emissions above water,” Dal Bó says.ĭearden is working with Fletcher Jones Foundation Professor of Chemistry Michael Hill on a project titled “The Electrochemical driven hydrocarbon oxidation by a cytochrome P450 BM3 (Bacillus megaterium)/anthraquinone conjugate.”ĭearden researches Cytochrome P450s, heme monoxidase enzymes that catalyze highly specific molecular alterations, which makes them invaluable tools in biomedicine and drug synthesis-including cancer drugs. Using molecular analyses, microscopy techniques and isotopic data, she aims to identify the microbes that form intimate partnerships with these animals and how they may be facilitating their unusual nutritional lifestyle. ![]() Working with Professor of Biology Shana Goffredi, Dal Bó will pursue a project titled “In Search of Methane-Oxidizing Symbionts in Deep-Sea Invertebrates.”ĭal Bó researches deep-sea invertebrates-specifically sponges, sea spiders, worms and snails-that inhabit the diverse ecosystem of the Del Mar methane seep off the coast of Southern California. Elam and former Science Scholar Elisabeth (Lisa) Rutledge '10. The committee also included President Harry J. The finalists interviewed with a faculty committee made up of Associate Professor of Chemistry Jeffrey Cannon, Professor of Physics Janet Scheel, Professor of Biology Joseph Schulz, Associate Professor of Cognitive Science and Computer Science Justin Li and Morrissey. “These scholars represent a special group who started Oxy during fully remote learning and faced additional obstacles in order to become successful researchers.” “The applicant pool was very strong this year,” says Undergraduate Research Center Director and Associate Professor of Philosophy Clair Morrissey. Each scholar will present their work at a professional conference as well as at Oxy's summer 2023 Undergraduate Research Conference. Mason Lynch ’24, a cell and molecular biology major and urban & environmental policy minor from San Jose and Ruby Siehl ’24, a biology (environmental science) major and sociology minor from Seattle.Įach Science Scholar receives $15,000 for research conducted during the spring term of their junior year, summer research between junior/senior years, and all of senior year. The scholars selected for this prestigious honor include Bianca Dal Bó ’24, a biology major and Latino/a & Latin American studies minor from Berkeley Clara Dearden ’24, a chemistry major from San Diego Ciara Gillen ’24, a chemistry major from Newton, Mass.
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